Overuse
and misuse of bacteria killers leave an open field for opportunistic
bacteria that would normally be kept in check by other germs.
These antibiotic-resistant bacteria have developed cunning ways
to foil even the strongest medications in some cases, says Levy.
He
recommends a return to older cleansers that leave no residues,
such as alcohol, chlorine bleach and hydrogen peroxide, as well
as time-tested soap and hot water. Strong antibacterial cleansers
make sense only when someone in the household is seriously ill
or has low immunity, he added. Then, caregivers should wash their
hands for at least a minute and leave antibacterial cleansers
on kitchen surfaces for minutes, not seconds.
Not
only is exposure to bacteria generally harmless, it is essential
for the normal development of a baby's immune system. According
to a recent Italian study, a baby during its first year must be
exposed to germs in order to develop antibodies necessary to fight
dangerous infections later in life. If the baby's environment
is too clean, the production of T-helper 1 cells is not adequately
stimulated and the immune system overproduces T-helper 2 cells,
which in turn make antibodies to fight allergens. That imbalance
of T-helper cells could result in lifelong allergies or asthma.
"Just
as a child needs lots of exercise to develop strong bones and
muscles, a child's immune system needs a rigorous workout to develop
normal resistance to infections throughout life," says Levy,
who also directs the Tuft's Center for Adaptation Genetics and
Drug Resistance. The center focuses on finding solutions to the
problem of antibiotic resistance.
Infectious
diseases are the leading cause of death worldwide, and the third
leading cause of death in the United States, following heart disease
and strokes. Because many bacteria have learned to evade some
or all of the 100 or so antibiotics developed in the last 60 years
to fight them, deaths from infectious diseases like tuberculosis
are once again on the rise. So concerned are leaders of the World
Health Organization, American College of Physicians, the American
Medical Association and the U.S. Centers for Disease Control and
Prevention that they recently named antibiotic resistance as one
of the top public health concerns of this decade.
"In
the United States, we now have at least five organisms with strains
that are resistant to all antibiotics that are available, including
the drug vancomycin, which has been considered to be the last
line of defense against drug-resistant infections," he says.
"New antibiotic development lags several years behind the
need, so there is no magic bullet around the corner. If we are
to avert a crisis, people need to stop and think twice before
using fortified cleansers and pressuring their doctors to give
them antibiotics for every infection."
A
truce with harmless bacteria is a good first step toward a solution.
"Bacteria are a natural and needed part of life," says
Levy. "Most live blamelessly. In fact, they often protect
us from disease because they compete with and thus limit the proliferation
of pathogenic bacteria. The benign competitors can be important
allies in the fight against antibiotic-resistant pathogens."
Note:
This article has been adapted from a news release issued by
American Society For Microbiology for journalists and other members
of the public. If you wish to quote from any part of this story
about drug-resistant bacteria, please credit American Society
For Microbiology as the original source. This
article was published by Science Daily, www.sciencedaily.com.
Comment:
This article on drug-resistant bacteria explains why some
of the healthiest people live a life where they are exposed to
many germs. Drug-resistant bacteria are not so scary when you
have a healthy immune system. Sally Robertson
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