Research
Boost Immune System
Searching For Meaning In Life May Boost Immune System
4-29-2003
Pursuing goals related to living a meaningful life may boost
the activity of certain cells in the immune system, according
to a small study of women who lost a relative to breast
cancer.
Women
who placed more importance on these goals at the beginning
of the study had higher levels of activity among their "natural
killer" immune cells. In addition, women who elevated
the importance of these goals over a one-month period showed
increases in natural killer cell activity, compared to women
who said that the importance of these goals had decreased
for them.
Some
of the women in the study were asked to write essays about
their loss in an attempt to discover whether this activity
might change life goals and boost immune activity, but the
researchers concluded that the writing exercise itself was
not associated with changes in either.
The
next step will be to uncover the ways in which "finding
meaning gets 'under the skin' and influences the immune
system," say Julienne E. Bower, Ph.D., of the University
of California, Los Angeles and colleagues.
Previous
research has shown a strong link between stressful events
and immune system functioning, while other studies suggest
that some individuals find positive meaning after a stressful
event. Bower and colleagues wanted to test whether writing
about a stressful event might produce positive psychological
changes that could in turn affect the immune system.
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For four weeks, half of the women in the study wrote
essays about their experience with the loss of a relative from breast
cancer, while the other half wrote about non-emotional experiences.
The women also answered a series of questions about their life goals
and had blood drawn before and after the essay series to monitor changes
in their natural killer cells.
Some of the women in the study said that they had
increased interest in personal development, relationship building
and "striving for meaning in my life" after a month, but
these changes were not related to whether they had written about a
traumatic or non-emotional event, the researchers say.
The study was published in the Annals of Behavioral
Medicine and supported by the Norman Cousins Program in Psychoneuroimmunology
at the University of California, the National Institute of Mental
Health and the National Science Foundation.
This story has been adapted from a news release issued
by Center For The Advancement Of Health, www.cfah.org.
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