Research
Immune System Disease
Fighting Ability
Part 3

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The following are articles about research on the ability of the immune system to fight diseases. This section includes some of the latest research on finding a cancer vaccine:

Article 17: Scientists Identify Cell Defects That Limit Immune System's Impact On Late-stage Tumors Although vaccines developed to help the immune system fight tumors appear to have an impact against early-stage tumors, they have little if any success in slowing the growth of tumors in later stages. Now researchers identify abnormalities in the immune system disease fighting capability and describe how the defects might be detected and repaired...

Article 16: Study Evaluates Immune Response To Telomerase Tumor Antigen As Possible Breast Cancer Vaccine Researchers have begun a clinical trial to evaluate the effectiveness of a telomerase peptide as a possible vaccine against breast cancer. The study will measure potential tumor cell shrinkage in patients after an immune system disease fighting response has been triggered to an antigen found in more than 90 percent of breast cancer tumors...

Article 15: Study By UCSD Gives New Insight Into How Anthrax Bacteria Can Evade A Host's Immune Response Biologists at the University of California, San Diego have determined how toxin produced by anthrax bacteria blocks a person's normal immune system disease fighting response, a discovery that could lead to new treatments for anthrax infection...

Article 14: Ebola Virus-like Particles Prevent Lethal Ebola Virus Infection Scientists have successfully immunized mice against Ebola virus using hollow virus-like particles, or VLPs, which are non-infectious but capable of provoking a robust immune system disease fighting response...

Article 13: HIV Vaccine In Worldwide Trial Vanderbilt University Medical Center is participating in worldwide tests of a potential vaccine that can stimulate important immune system disease fighting responses against the virus that causes AIDS. This is the first candidate vaccine against the human immunodeficiency virus (HIV) to be studied simultaneously in so many locations, from Brazil to Thailand...

Article 12: Emory Researchers Discover Novel Mechanism Of How Anthrax Impairs Immunity Researchers have shown that anthrax lethal factor (LF) impairs the function of dendritic cells and thereby compromises the immune system disease fighting ability. The findings have implications for developing more effective anthrax therapies and guiding researchers in better controlling detrimental immune responses...

Article 11: Cancer Vaccine One Step Closer Andreea Ioan-Facsinay has attached proteins from tumour cells to antibodies. With these she treated immune cells from a mouse. These treated cells were used to make a vaccine, which was shown to be effective in animal experiments. If the follow-up research is successful, vaccines against cancer will become available...

Article 10: New Hope For Vaccine To Fight Rheumatoid Arthritis, Other Autoimmune Diseases Promising animal test results that could lead to a vaccine to fight rheumatoid arthritis, multiple sclerosis (MS) and other autoimmune diseases were announced by researchers. The vaccine reversed an arthritic-like disease in rats by mobilizing part of the immune system to protect joints under attack by other immune cells...

Article 9: Researchers Identify A Gene Essential For The Natural Killer Cell Response Against Cancer The innate immune response must defend the body against onslaughts from foreign substances it has never before seen. Failure of this immune system disease fighting component can result in cancer, autoimmune disease, or life threatening viral infections...

Article 8: Rare Disorder Provides New Insight Into Fighting Infection Through studying a genetic condition known to exist in only two individuals, scientists have uncovered new knowledge about the immune system disease fighting ability that is applicable to everyone. The scientists found that an enzyme called caspase-8, known to help trigger apoptosis (the programmed death of cells) is also involved in activating many immune system cells to fight off disease...

Article 7: Brain Cancer Vaccine Shows Promising Findings In Early Research At UCLA's Jonsson Cancer Center An experimental vaccine for brain cancer has shown promising results in preliminary investigations. The vaccine completely prevented brain tumor formation in laboratory rats. In contrast, all of the rats that did not receive the vaccine did not have the same immune system disease fighting ability because they developed very aggressive brain tumors...

Article 6: DNA Arrays Give Clues To Better Vaccines The methods researchers use to study microbes has changed. Now they do not have to just watch cultures of pathogens as the only way to see what they are doing. Scientists are now able to listen to the cross talk between invading pathogens and the immune system disease fighting cells...

Article 5: Researchers Find How Tuberculosis Bacterium Evades Detection By Immune System Tuberculosis (TB) is one of the scourges of humans, infecting about one-third of the world's population, or two billion people. It kills an estimated eight million people annually. A new researched project reveals how the tuberculosis bacterium evades detection by the body's immune system disease fighting cells...

Article 4: Methadone Promotes HIV Infection In Cell Culture Methadone, the drug that is widely used in drug treatment centers to treat heroin addicts, stimulates HIV infection of human immune cells studied in cell cultures. The researchers proposed that HIV-infected patients receiving methadone to treat drug abuse should have their blood and immune system disease fighting status watched for possible adverse effects of the treatment...

Article 3: Pancreatic Cancer Vaccine Found Safe In Early Study Hopkins researchers say early tests of a pancreatic cancer vaccine show it is safe and successful in reaching immune system disease fighting cells. The vaccine, tested on 14 patients, uses lab-grown pancreatic cancer cells genetically-modified with the immune-boosting gene GM-CSF...

Article 2: Researchers Successfully Immunize Mice Against Aggressive Cancer So far, immunized mice have survived for as long as 150 days after exposure to active melanoma cells. Unprotected mice died in a matter of weeks. This has important implications for boosting the human immune disease fighting ability to ward off cancer...

Article 1: Human Immune System Defenseless Against New Hong Kong Flu-Highly Unusual Infection Direct From Poultry Typically, new influenza viruses pass through and are genetically modified in other mammals, like pigs, before reaching humans. A unique feature of this new virus is that it managed to cross the avian-human species barrier without prior adaptation in another mammalian species. Humans do not have the immune system disease fighting ability to ward it off...